CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13582
Family Name Ghrelin/growth hormone secretagogue receptor and Cytochrome P450 2D6 ligand 6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]quinazolin-4-one family
No. of Seeds 5 No. of Other Members 20
Family Centroid CFAMM00380417 Functional Category Bioactive with Natural Product
Superfamily Vasopressin V1b receptor and Beta-secretase 1 Binder Superfamily
Class Class 1457

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Extracellular calcium-sensing receptor Ligand 2-furan-2-yl-3-p... 4 119
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxy-phenyl)-... 1 3
Poly [ADP-ribose] polymerase 1 Inhibitor 8-methoxy-2-phenyl-3h... 4 6
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 28 91
Beta-secretase 1 inhibitor SureCN8235614 family 4 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
Vasopressin V1b receptor ligand AGN-PC-09QGT9 family 4 123
Vasopressin V1b receptor ligand AGN-PC-00HJ2S family 4 6
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 2 3
C-X-C chemokine receptor type 3 ligand N-(2-ethoxyethyl)-N-[(1... 1 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 16 2
Histamine H3 receptor ligand AGN-PC-03Z8FM family 5 0
Histamine H3 receptor ligand AGN-PC-00AE5Q family 13 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Histamine H3 receptor ligand AGN-PC-03Z8HJ family 4 1
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5
Multidrug resistance protein 1B and Multidrug resistance-assoc... 1 4
Adenosine receptor A2a and Amine oxidase [flavin-containing] B... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423062 CHEMBL429817 Bioactive 6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidin-3-ylmethyl)quinazolin-4-one
CFAMM00423048 CHEMBL242999 Bioactive AGN-PC-046IAD
CFAMM00423064 CHEMBL242566 Bioactive 6-(4-fluorophenoxy)-2-propan-2-yl-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]quinazolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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