CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13583
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor SureCN13425075 family
No. of Seeds 13 No. of Other Members 9
Family Centroid CFAMM00423073 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B and B2 bradykinin receptor Binder Superfamily
Class Class 4628

Cousin Family NamesSeedsMembers
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor Sure... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-... 2 0
Poly [ADP-ribose] polymerase 1 inhibitor 1-(4-methoxyphenyl)-3... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor AGN-PC-07ZCRO family 1 2
Cyclin-dependent kinase 2 inhibitor N-[(4-chlorophenyl)carbamo... 3 0


External ID

Functional Category

Molecule Name

CFAMM00423089 CHEMBL2425750 Bioactive AGN-PC-0CT7LG
CFAMM00423071 CHEMBL2425761 Bioactive AGN-PC-0CT7L4
CFAMM00423085 CHEMBL2425754 Bioactive 2-cyclopropyl-N-(3,5-dichloro-1-hydroxypyridin-4-ylidene)-7-methoxypyrazolo[1,5-a]pyridine-4-carboxamide
CFAMM00423070 CHEMBL2425760 Bioactive (2Z)-N-(3,5-dichloropyridin-4-yl)-7-methoxy-2-(nitrosomethylidene)-1H-pyrazolo[1,5-a]pyridine-4-carboxamide
CFAMM00423083 CHEMBL2425758 Bioactive AGN-PC-0CT7LE
CFAMM00423074 CHEMBL2425746 Bioactive SureCN13425108
CFAMM00423082 CHEMBL2425759 Bioactive AGN-PC-0CT7LD
CFAMM00423091 CHEMBL2425752 Bioactive N-(3,5-dichloro-1-hydroxypyridin-4-ylidene)-7-methoxy-2-propan-2-ylpyrazolo[1,5-a]pyridine-4-carboxamide
CFAMM00423073 CHEMBL2425749 Bioactive SureCN13425075
CFAMM00423081 CHEMBL2425753 Bioactive SureCN13425085
CFAMM00423090 CHEMBL2425775 Bioactive AGN-PC-0CT7L9
CFAMM00423072 CHEMBL2425748 Bioactive AGN-PC-0CT7L3
CFAMM00423080 CHEMBL2425738 Bioactive SureCN13425131

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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