CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13606
Family Name Glucocorticoid receptor ligand 3-(1H-indol-5-yl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00423258 Functional Category Bioactive
Superfamily Glucocorticoid receptor Binder Superfamily 11
Class Class 170

Cousin Family NamesSeedsMembers
mRNA of Glucagon receptor Ligand Isis 325568 Family 1 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Mitogen-activated protein kinase 14 inhibitor 6-[3-amino-5-(2-... 4 9
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 1 1
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 5 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
D(3) dopamine receptor and D(2) dopamine receptor ligand 6-N-[... 3 0
Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-... 1 2
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 6 1
Glucocorticoid receptor ligand 3-[1-(3-chloro-4-fluorophenyl)i... 2 0
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)indazol-5-... 16 10
Glucocorticoid receptor ligand (3R)-3-[1-(4-fluorophenyl)indaz... 4 2
MAP kinase-activated protein kinase 2 inhibitor 2-[(4,4-dimeth... 11 11
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 1
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Methionine aminopeptidase 1 inhibitor N-[5-[2-oxo-2-[4-(2-pyri... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423258 CHEMBL2426152 Bioactive 3-(1H-indol-5-yl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
CFAMM00423251 CHEMBL276271 Bioactive (6aR,9R,10aR)-3-tert-butyl-7-methyl-N-(1,3-thiazol-2-yl)-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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