CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13608
Family Name C-C motif chemokine 2 inhibitor (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-[(5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)amino]-1-propan-2-ylcyclopentane-1-carboxamide family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00423270 Functional Category Bioactive
Superfamily C-C motif chemokine 2 and C-C chemokine receptor type 2 Binder Superfamily
Class Class 609

Cousin Family NamesSeedsMembers
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 10
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 1


External ID

Functional Category

Molecule Name

CFAMM00423271 CHEMBL2426335 Bioactive (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-(6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-7-ylamino)-1-propan-2-ylcyclopentane-1-carboxamide
CFAMM00423270 CHEMBL2426334 Bioactive (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-[(5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)amino]-1-propan-2-ylcyclopentane-1-carboxamide
CFAMM00423269 CHEMBL2426351 Bioactive (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-[(5-methoxy-2,3-dihydro-1H-inden-1-yl)amino]-1-propan-2-ylcyclopentane-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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