CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13610
Family Name Deoxycytidine kinase inhibitor 2-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]ethanol family
No. of Seeds 14 No. of Other Members 11
Family Centroid CFAMM00423289 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 103
Class Class 4998

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydro... 1 3
Receptor-type tyrosine-protein kinase FLT3 ligand 2-(6,7-dimet... 3 2
Survival motor neuron protein and Microtubule-associated prote... 1 20
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Histone-lysine N-methyltransferase EHMT2 inhibitor N-(1-cyclop... 1 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 1
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
Vascular endothelial growth factor receptor 2 ligand aminothia... 1 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 2
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
DNA-(apurinic or apyrimidinic site) lyase and DNA polymerase b... 1 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


External ID

Functional Category

Molecule Name

CFAMM00423289 CHEMBL2426570 Bioactive 2-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]ethanol
CFAMM00423292 CHEMBL2426573 Bioactive 1-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]-2-methylpropan-2-ol
CFAMM00423274 CHEMBL2426569 Bioactive 3-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]propan-1-ol
CFAMM00423280 CHEMBL2426564 Bioactive 2-[3-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-5-fluorophenoxy]ethanol
CFAMM00423288 CHEMBL2426574 Bioactive N-[2-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]ethyl]methanesulfonamide
CFAMM00423291 CHEMBL2426558 Bioactive 2-[[2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-propyl-1,3-thiazol-4-yl]methylsulfanyl]pyrimidine-4,6-diamine
CFAMM00423279 CHEMBL2426566 Bioactive N-[2-[3-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-5-fluorophenoxy]ethyl]methanesulfonamide
CFAMM00423278 CHEMBL2426567 Bioactive 2-[4-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-(2-hydroxyethoxy)phenoxy]ethanol
CFAMM00423296 CHEMBL2426572 Bioactive 1-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]propan-2-ol
CFAMM00423277 CHEMBL2426562 Bioactive 2-[3-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]phenoxy]ethanol
CFAMM00423276 CHEMBL2426563 Bioactive 2-[5-[4-[(4,6-diaminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-fluorophenoxy]ethanol
CFAMM00423290 CHEMBL2426571 Bioactive 2-[5-[4-[(4-aminopyrimidin-2-yl)sulfanylmethyl]-5-propyl-1,3-thiazol-2-yl]-2-methoxyphenoxy]ethanol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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