CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13613
Family Name Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-4-phenyl-N-(1,3,4-thiadiazol-2-yl)butanamide family
No. of Seeds 16 No. of Other Members 10
Family Centroid CFAMM00423319 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Kinesin-like protein KIF11 Binder Superfamily
Class Class 1276

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Adenosine receptor A3 ligand AGN-PC-07N4XY family 2 2
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(7-aminop... 1 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 2 1
Metabotropic glutamate receptor 5 and Metabotropic glutamate r... 1 16
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 6 1
Glucocorticoid receptor ligand 3-(1H-indol-5-yl)-2,2-dimethyl-... 2 7
Glucocorticoid receptor ligand (3R)-3-[1-(4-fluorophenyl)indaz... 4 2
Glucocorticoid receptor ligand 3-[1-(4-methoxyphenyl)indazol-5... 2 1
Glucocorticoid receptor ligand (3S)-3-(1H-indazol-5-yl)-2,2-di... 1 0
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 1 0


External ID

Functional Category

Molecule Name

CFAMM00423314 CHEMBL2426636 Bioactive 3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-N-(1,3,4-thiadiazol-2-yl)hexanamide
CFAMM00423304 CHEMBL2426660 Bioactive 2,2-dimethyl-3-phenyl-3-(1-phenylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423320 CHEMBL2426638 Bioactive 3-[1-(4-fluorophenyl)indazol-5-yl]-2,2,5-trimethyl-N-(1,3,4-thiadiazol-2-yl)hexanamide
CFAMM00423313 CHEMBL2426637 Bioactive 3-[1-(4-fluorophenyl)indazol-5-yl]-2,2,4-trimethyl-N-(1,3,4-thiadiazol-2-yl)pentanamide
CFAMM00423326 CHEMBL2426656 Bioactive 2,2-dimethyl-3-[1-(3-methylbutyl)indazol-5-yl]-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423319 CHEMBL2426639 Bioactive 3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-4-phenyl-N-(1,3,4-thiadiazol-2-yl)butanamide
CFAMM00423309 CHEMBL2426647 Bioactive 2,2-dimethyl-3-phenyl-3-(1-pyridin-2-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423312 CHEMBL2426649 Bioactive (3R)-2,2-dimethyl-3-phenyl-3-(1-pyridin-3-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423302 CHEMBL2426624 Bioactive (3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2-methyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423311 CHEMBL2426648 Bioactive (3S)-2,2-dimethyl-3-phenyl-3-(1-pyridin-3-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423324 CHEMBL2426650 Bioactive 2,2-dimethyl-3-phenyl-3-(1-pyridin-4-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423301 CHEMBL2426623 Bioactive AGN-PC-04UBRZ
CFAMM00423307 CHEMBL2426663 Bioactive (3R)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423310 CHEMBL2426645 Bioactive 3-[1-(4-chlorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423306 CHEMBL2426662 Bioactive (3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
CFAMM00423322 CHEMBL2426654 Bioactive 2,2-dimethyl-3-phenyl-3-(1-propan-2-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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