CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1362
Family Name Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[(2R)-1-(1,1-dioxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)-1-oxo-5-phenylpentan-2-yl]-2-methylpropanamide family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00322558 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Ligand AZD5672 Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Cruzipain Inhibitor K-777 Family 3 8
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Prolyl endopeptidase inhibitor SureCN194654 family 3 4
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322559 CHEMBL1161832 Bioactive 2-amino-N-[(2R)-1-(1,1-dioxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)-1-oxo-4-phenylbutan-2-yl]-2-methylpropanamide
CFAMM00322558 CHEMBL1161828 Bioactive 2-amino-N-[(2R)-1-(1,1-dioxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)-1-oxo-5-phenylpentan-2-yl]-2-methylpropanamide
CFAMM00322562 CHEMBL1161827 Bioactive 2-amino-2-methyl-N-[(2R)-1-oxo-1-(1-oxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)-5-phenylpentan-2-yl]propanamide
CFAMM00322561 CHEMBL1161822 Bioactive 2-amino-2-methyl-N-[(2R)-1-oxo-5-phenyl-1-spiro[2H-1-benzothiophene-3,4'-piperidine]-1'-ylpentan-2-yl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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