CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1365
Family Name Growth hormone secretagogue receptor type 1 ligand 2-amino-2-methyl-N-[(2R)-1-oxo-3-phenylmethoxy-1-spiro[2H-1-benzofuran-3,4'-piperidine]-1'-ylpropan-2-yl]propanamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00322570 Functional Category Bioactive
Superfamily Histamine H3 receptor and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Lopinavir Family 4 25
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Pol polyprotein inhibitor 180968-31-4 family 8 13
Histamine H3 receptor ligand SureCN4319687 family 8 15
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 13
E3 ubiquitin-protein ligase XIAP inhibitor N-METHYLALANYL-3-ME... 3 14
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 4
Pol polyprotein inhibitor MDL 74538 family 11 1
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21e family 6 7
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
Motilin receptor ligand SureCN74051 family 1 0
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Renin inhibitor (2S,4S,5S,7S)-5-amino-4-hydroxy-7-[[4-methoxy-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322570 CHEMBL1161831 Bioactive 2-amino-2-methyl-N-[(2R)-1-oxo-3-phenylmethoxy-1-spiro[2H-1-benzofuran-3,4'-piperidine]-1'-ylpropan-2-yl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48707 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543