CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13652
Family Name Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[[2-[(3-iodanylbenzoyl)amino]acetyl]amino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00423497 Functional Category Bioactive
Superfamily Iofolastat I-124 Superfamily
Class Class 1231

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
Iofolastat I-124 family 6 33
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
Angiotensin-converting enzyme and Histone-lysine N-methyltrans... 1 19
Integrin beta-1 and Integrin alpha-4 inhibitor (3S,6R,11R,14S)... 2 0
NP Methyl 5-((2s,3s,4r)-4-benzamido-3-chlorotetrahydrothiophen... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423495 CHEMBL2431338 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[5-[[2-[(3-iodobenzoyl)amino]acetyl]amino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423494 CHEMBL2431340 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[4-[(3-iodobenzoyl)amino]butanoylamino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423500 CHEMBL2431337 Bioactive (2S)-2-[[(1R)-2-[1-[(5S)-5-[(2-benzamidoacetyl)amino]-5-carboxypentyl]-2,5-dioxopyrrolidin-3-yl]sulfanyl-1-carboxyethyl]carbamoylamino]pentanedioic acid
CFAMM00423493 CHEMBL2431341 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[5-[(3-iodobenzoyl)amino]pentanoylamino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423499 CHEMBL2431336 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[[2-[(3-iodobenzoyl)amino]acetyl]amino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423498 CHEMBL2431330 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[(3-iodobenzoyl)amino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423497 CHEMBL2431333 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[[2-[(3-iodanylbenzoyl)amino]acetyl]amino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid
CFAMM00423496 CHEMBL2431339 Bioactive (2S)-2-[[(1R)-1-carboxy-2-[1-[(5S)-5-carboxy-5-[3-[(3-iodobenzoyl)amino]propanoylamino]pentyl]-2,5-dioxopyrrolidin-3-yl]sulfanylethyl]carbamoylamino]pentanedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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