CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13664
Family Name Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ligand SureCN13986096 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00291198 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Inositol monophosphatase 1 Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 28 24
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-fluoro-N-[4-me... 2 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 3-... 4 8
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 3 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Sonic hedgehog protein inhibitor 3-methoxy-1-methyl-4-oxo-5-ph... 5 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 7-met... 3 2
Substance-P receptor ligand AGN-PC-01VLKE family 9 11
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 2 1
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Vasopressin V2 receptor ligand SureCN4400636 family 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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