CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13668
Family Name Serine/threonine-protein kinase Chk1 inhibitor 2-[9-(4-amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-2-yl]-2-methyl-N-(4-morpholin-4-ylphenyl)propanamide family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00423585 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 1 Binder Superfamily
Class Class 1583

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Microsomal triglyceride transfer protein large subunit inhibit... 3 0
5-hydroxytryptamine receptor 1B ligand SureCN5352760 family 2 5
Poly [ADP-ribose] polymerase 1 inhibitor N-ethyl-4-[4-[(8-meth... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 9-(4-amino-3-me... 3 7
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 2
Serine/threonine-protein kinase Chk1 inhibitor 2,3-dimethoxy-9... 15 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN4849127 f... 4 1
Vascular endothelial growth factor receptor 2 ligand CHEMBL197... 1 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4856064 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423583 CHEMBL243499 Bioactive 3-[9-(4-amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)propanamide
CFAMM00423587 CHEMBL540992 Bioactive SureCN4849692
CFAMM00423586 CHEMBL389745 Bioactive 2-[9-(4-amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-2-methyl-N-(4-morpholin-4-ylphenyl)propanamide
CFAMM00423585 CHEMBL387787 Bioactive 2-[9-(4-amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-2-yl]-2-methyl-N-(4-morpholin-4-ylphenyl)propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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