CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13677
Family Name C-C chemokine receptor type 5 ligand N-methyl-4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00423637 Functional Category Bioactive
Superfamily P2Y purinoceptor 12 and C-C chemokine receptor type 5 Binder Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Histamine H3 receptor ligand SureCN2784306 family 5 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
NS5B protein inhibitor AC1O5AET family 3 1
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Microsomal triglyceride transfer protein large subunit inhibit... 9 0
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Disintegrin and metalloproteinase domain-containing protein 17... 5 4
C-C chemokine receptor type 5 and C-C chemokine receptor type ... 7 0
Disintegrin and metalloproteinase domain-containing protein 17... 5 0
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423635 CHEMBL2435858 Bioactive 4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide
CFAMM00423637 CHEMBL2435843 Bioactive N-methyl-4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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