CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1368
Family Name Purine nucleoside phosphorylase inhibitor 2-amino-7-[[(2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00322588 Functional Category Bioactive
Superfamily Purine nucleoside phosphorylase Binder Superfamily
Class Class 1306

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Purine nucleoside phosphorylase inhibitor 7-[(3R,4S,5R)-3,4-di... 10 34
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 17 17
Purine nucleoside phosphorylase inhibitor 2-amino-6-benzyl-1,7... 3 2
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Purine nucleoside phosphorylase inhibitor 3-[(2S,3S,4R,5R)-3,4... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 1
Purine nucleoside phosphorylase inhibitor SureCN6345422 family 9 11
Purine nucleoside phosphorylase inhibitor (3s)-3-(2-amino-4-hy... 2 0
Purine nucleoside phosphorylase inhibitor SureCN6353628 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322587 CHEMBL543401 Bioactive 7-[[(2R,3S)-3,4-dihydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one;hydrochloride
CFAMM00322586 CHEMBL435085 Bioactive SureCN12715838
CFAMM00322585 CHEMBL1161895 Bioactive acetic acid;2-amino-7-[[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
CFAMM00322584 CHEMBL1161900 Bioactive acetic acid;2-amino-7-[[bis(2-hydroxyethyl)amino]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
CFAMM00322588 CHEMBL385263 Bioactive 2-amino-7-[[(2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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