CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13685
Family Name E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhibitor (2S)-N-[(3S)-1-benzoyl-5-[(6-bromo-2-methoxynaphthalen-1-yl)methyl]-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00423691 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and E3 ubiquitin-protein ligase XIAP Binder Superfamily
Class Class 4802

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 2
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 0
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 4 2
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 0
D(3) dopamine receptor and D(4) dopamine receptor ligand SureC... 3 19
Sigma non-opioid intracellular receptor 1 and D(3) dopamine re... 26 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423690 CHEMBL2436331 Bioactive (2S)-N-[(3S)-5-[(6-bromo-2-methoxynaphthalen-1-yl)methyl]-1-(4-fluorobenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride
CFAMM00423687 CHEMBL2436334 Bioactive (2S)-N-[(3S)-5-[(6-bromo-2-methoxynaphthalen-1-yl)methyl]-1-(4-methylbenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride
CFAMM00423698 CHEMBL2436205 Bioactive (2S)-N-[(3S)-5-[(6-bromo-2-methoxynaphthalen-1-yl)methyl]-1-(4-methylsulfonylbenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride
CFAMM00423691 CHEMBL2436330 Bioactive (2S)-N-[(3S)-1-benzoyl-5-[(6-bromo-2-methoxynaphthalen-1-yl)methyl]-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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