CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13686
Family Name E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhibitor (2S)-N-[(3S)-1-(4-aminobenzoyl)-5-[(2-methoxynaphthalen-1-yl)methyl]-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00423703 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and E3 ubiquitin-protein ligase XIAP Binder Superfamily
Class Class 4802

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Microsomal triglyceride transfer protein large subunit inhibit... 3 0
Serine/threonine-protein kinase Chk1 inhibitor 2-[9-(4-amino-3... 5 2
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 4 11
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 0
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 4 2
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423703 CHEMBL2436208 Bioactive (2S)-N-[(3S)-1-(4-aminobenzoyl)-5-[(2-methoxynaphthalen-1-yl)methyl]-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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