CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13693
Family Name Bifunctional epoxide hydrolase 2 inhibitor 8-(2-fluoro-5-hydroxybenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00314833 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Substance-K receptor Ligand MEN-14933 Family 13 154
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor Ligand Epidepride Family 31 66
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 1 9
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-087THW family 1 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 2 1
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 3 11
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-ethylbutanoyl)... 11 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4
Growth hormone secretagogue receptor type 1 ligand N-[4-[(2S)-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26235 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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