CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13695
Family Name Bifunctional epoxide hydrolase 2 inhibitor 8-(1H-benzimidazole-4-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00374331 Functional Category Bioactive
Superfamily TGF-beta receptor type-1 and Telomerase reverse transcriptase Binder Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Prothrombin inhibitor AGN-PC-09QMX4 family 1 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Hepatocyte growth factor receptor ligand 4-pyridone analogue, ... 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27624 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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