CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13698
Family Name Bifunctional epoxide hydrolase 2 inhibitor 8-(2-methylfuran-3-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00271198 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 Binder Superfamily 14
Class Class 2604

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Phospholipase D1 and Phospholipase D2 inhibitor 4,5-dibromo-N-... 1 3
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-ethylbutanoyl)... 11 0
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423724 CHEMBL2436581 Bioactive 8-(furan-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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