CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13699
Family Name Bifunctional epoxide hydrolase 2 inhibitor 8-(2-ethylbutanoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide family
No. of Seeds 11 No. of Other Members 0
Family Centroid CFAMM00190591 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Lethal factor Binder Superfamily
Class Class 2070

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-087THW family 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Transient receptor potential cation channel subfamily V member... 3 15
Carbonic anhydrase 12 and Probable transmembrane carbonic anhy... 2 0
Cathepsin S and Cathepsin K inhibitor SureCN3018173 family 2 4
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-fluoro-5-hydro... 2 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-methylfuran-3-... 2 1
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
C-X-C chemokine receptor type 3 ligand 1-[1-[[(1S,5R)-6,6-dime... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423727 CHEMBL2436589 Bioactive 8-(2-cyclopropylacetyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
CFAMM00423726 CHEMBL2436586 Bioactive N-[4-(trifluoromethoxy)phenyl]-8-[1-(trifluoromethyl)cyclopropanecarbonyl]-2,8-diazaspiro[4.5]decane-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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