CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1370
Family Name Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00322602 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Binder Superfamily 4
Class Class 1027

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Toll-like receptor 7 Ligand GS-9620 Family 2 4
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Dipeptidyl peptidase 4 inhibitor Xanthine mimetic compound 8 f... 2 2
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 4 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 11 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1... 1 0
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 1 0
Dipeptidyl peptidase 4 inhibitor 2-(3-aminopiperidin-1-yl)-3-b... 4 1
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKJ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322602 CHEMBL1161923 Bioactive AGN-PC-046QKE
CFAMM00322601 CHEMBL1161922 Bioactive Xanthine mimetic compound 9
CFAMM00322603 CHEMBL1161919 Bioactive Xanthine mimetic compound 7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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