CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13704
Family Name Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(8-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00423745 Functional Category Bioactive
Superfamily Histamine H3 receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 666

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mepyramine Family 5 65
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
5-hydroxytryptamine receptor 3A ligand 6-methyl-5-[4-[3-[(2R)-... 12 3
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Melanocortin receptor 4 ligand N-[(2R)-3-(2,4-dichlorophenyl)-... 2 2
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 4 9
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 5
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 1 0
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 5 1
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423745 CHEMBL2436624 Bioactive [1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(8-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone
CFAMM00423744 CHEMBL2436625 Bioactive [1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(7-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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