CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13721
Family Name Vascular endothelial growth factor receptor 2 and Angiopoietin-1 receptor ligand benzimidazole-urea, 24 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00423843 Functional Category Bioactive
Superfamily Nonstructural protein 1 and Angiopoietin-1 receptor Binder Superfamily
Class Class 420

Cousin Family NamesSeedsMembers
Potassium-transporting ATPase alpha chain 1 Inhibitor Rabepraz... 4 113
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[5-chloro-2-[(6-m... 1 7
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 1 0
Cytochrome P450 2C19 and Cytochrome P450 1A2 inhibitor 2-hepty... 4 4


External ID

Functional Category

Molecule Name

CFAMM00423843 CHEMBL244096 Bioactive benzimidazole-urea, 24
CFAMM00423842 CHEMBL244095 Bioactive benzimidazole-urea, 23
CFAMM00423847 CHEMBL243908 Bioactive GW694234A

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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