CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13725
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butylsulfonylamino)-3-[(3-pyridin-4-yl-3-azaspiro[5.5]undecane-9-carbonyl)amino]propanoic acid family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00423860 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 14
Class Class 1127

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Prothrombin Inhibitor Ximelegatran Family 8 157
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Beta-secretase 1 inhibitor 1-N-[(1S,2S)-3-(3,5-difluorophenyl)... 2 16
Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido... 2 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7146965... 1 1
Pol polyprotein inhibitor 169168-47-2 family 4 0
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7152283... 2 1
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S,4R)... 2 2
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 1 0
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4
Prothrombin inhibitor N-[(1S)-2-[4-(2-fluoroethyl)piperidin-1-... 5 0
P2X purinoceptor 7 inhibitor AGN-PC-015BSR family 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 2 0
Prothrombin inhibitor 2-[(3S)-4-[4-(2-fluoroethyl)piperidin-1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423858 CHEMBL285835 Bioactive SureCN7011630
CFAMM00423860 CHEMBL24397 Bioactive (2S)-2-(butylsulfonylamino)-3-[(3-pyridin-4-yl-3-azaspiro[5.5]undecane-9-carbonyl)amino]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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