CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13727
Family Name Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00ES9G family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00423866 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily 13
Class Class 142

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Acolbifene family 10 115
Oestrogen receptor and Tyrosine-protein phosphatase non-recept... 92 21
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Renin Inhibitor Ro-65-7219 Family 10 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Estrogen receptor and Estrogen receptor beta ligand SureCN3115... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Estrogen receptor and Estrogen receptor beta ligand SureCN8476... 2 1


External ID

Functional Category

Molecule Name

CFAMM00423872 CHEMBL535158 Bioactive (5R)-7,9-difluoro-5-[4-(2-piperidin-1-ylethoxy)phenyl]-5H-naphtho[1,2-c]chromen-2-ol;hydrochloride
CFAMM00423871 CHEMBL243999 Bioactive SureCN14503677
CFAMM00423869 CHEMBL390021 Bioactive 6-(3-fluorophenyl)-5-[4-(2-piperidin-1-ylethoxy)phenoxy]naphthalen-2-ol
CFAMM00423868 CHEMBL537638 Bioactive AGN-PC-00ES9F
CFAMM00423867 CHEMBL244206 Bioactive SureCN10306628
CFAMM00423866 CHEMBL244205 Bioactive AGN-PC-00ES9G

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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