CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13738
Family Name Rho-associated protein kinase 2 inhibitor 2-hydroxyethyl 3-[2-(aminomethyl)-5-[(3-fluoropyridin-4-yl)carbamoyl]phenyl]benzoate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00423941 Functional Category Bioactive
Superfamily Caspase-1 and Cytochrome P450 3A4 Binder Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Coagulation factor X Inhibitor Otamixaban Family 9 21
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Coagulation factor X inhibitor (2S)-(3'-AMIDINO-3-BIPHENYL)-5-... 1 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QM95 family 1 1
B1 bradykinin receptor ligand AGN-PC-00CTAF family 1 3
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 2
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00423941 CHEMBL2440735 Bioactive 2-hydroxyethyl 3-[2-(aminomethyl)-5-[(3-fluoropyridin-4-yl)carbamoyl]phenyl]benzoate
CFAMM00423940 CHEMBL2440737 Bioactive oxolan-2-ylmethyl 3-[2-(aminomethyl)-5-[(3-fluoropyridin-4-yl)carbamoyl]phenyl]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543