CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1374
Family Name Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase inhibitor [(2R,3S,4R,5R)-5-(6-aminopurin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate family
No. of Seeds 24 No. of Other Members 9
Family Centroid CFAMM00322624 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor Ligand Cgp 20712a Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Poly [ADP-ribose] polymerase 1 Inhibitor EB-47 Family 17 41
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 9
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 3 0
Enterobactin synthase component E inhibitor [(2,3-dihydroxyben... 1 8
Adenosine receptor A3 ligand SureCN6211758 family 5 10
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 4
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 2
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 6 17
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 0
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 11 4
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
Adenosine receptor A1 ligand 3-chloro-N-[(2S,3R,4R,5R)-5-[6-(c... 1 0
P2X purinoceptor 1 and P2X purinoceptor 3 inhibitor [(2R,3R,4R... 1 5
Adenosine receptor A1 and Adenosine receptor A3 ligand ethyl 4... 2 0
Adenosine receptor A1 ligand (2,5-dioxopyrrolidin-1-yl) 2-[4-[... 3 0
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 1 0
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) ... 30 0
Equilibrative nucleoside transporter 1 inhibitor methyl 4-[[9-... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322646 CHEMBL609108 Bioactive [(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322633 CHEMBL612056 Bioactive N,N-diethylethanamine;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(propylamino)purin-9-yl]oxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate
CFAMM00322626 CHEMBL608841 Bioactive [(2R,3S,4R,5R)-5-(6-amino-2-phenylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322652 CHEMBL461568 Bioactive sodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(propan-2-ylamino)purin-9-yl]oxolan-2-yl]methoxysulfonyl-(2-hydroxybenzoyl)azanide
CFAMM00322632 CHEMBL609097 Bioactive N-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfamoyl]-2-hydroxybenzamide;N,N-diethylethanamine
CFAMM00322645 CHEMBL612022 Bioactive [(2R,3S,5R)-5-(6-aminopurin-7-yl)-3-hydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322625 CHEMBL608844 Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322638 CHEMBL1162040 Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-fluoro-6-hydroxybenzoyl)sulfamate
CFAMM00322651 CHEMBL609107 Bioactive [(1R,2R,3S,4R)-4-(6-aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322631 CHEMBL456074 Bioactive sodium;[(2R,3S,4R,5R)-5-[6-amino-2-(4-phenylphenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxysulfonyl-(2-hydroxybenzoyl)azanide
CFAMM00322644 CHEMBL612046 Bioactive [(2R,3S,4R,5R)-5-(6-amino-2-azidopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322624 CHEMBL220160 Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate
CFAMM00322637 CHEMBL518346 Bioactive sodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methoxysulfonyl-(2-hydroxybenzoyl)azanide
CFAMM00322650 CHEMBL218023 Bioactive [(1R,2R,3S,4R)-4-(6-aminopurin-7-yl)-2,3-dihydroxycyclopentyl]methyl N-(2-hydroxybenzoyl)sulfamate
CFAMM00322643 CHEMBL1627105 Bioactive sodium;[(2R,3S,4R,5R)-5-[6-amino-2-(3-phenylphenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxysulfonyl-(2-hydroxybenzoyl)azanide
CFAMM00322636 CHEMBL516501 Bioactive sodium;[(2R,3S,4R,5R)-5-[6-(ethylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxysulfonyl-(2-hydroxybenzoyl)azanide
CFAMM00322649 CHEMBL387162 Bioactive [(2S,4R,5R)-5-(6-aminopurin-7-yl)-4-hydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate
CFAMM00322629 CHEMBL612053 Bioactive [(2R,3S,4R,5R)-5-[6-(cyclopropylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322642 CHEMBL371502 Bioactive Salicyl-AMS
CFAMM00322635 CHEMBL218683 Bioactive N-[[(2R,3S,4R,5R)-5-(6-aminopurin-7-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfamoyl]-2-hydroxybenzamide
CFAMM00322648 CHEMBL611777 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(2-phenylethynyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322647 CHEMBL611771 Bioactive [(2R,3S,4R,5R)-5-(6-amino-2-anilinopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322627 CHEMBL611786 Bioactive [(2S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00322640 CHEMBL611789 Bioactive [(2R,3S,4R,5R)-5-(6-amino-2-iodopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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