CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13740
Family Name Prothrombin and Coagulation factor X inhibitor N-[3-[(3-fluorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00349535 Functional Category Bioactive
Superfamily Calcium-activated potassium channel subunit alpha-1 Ligand AVE0118 Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Neuronal acetylcholine receptor subunit beta-4 and Neuronal ac... 6 4
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 5
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 3 3
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Mitogen-activated protein kinase 14 inhibitor 3-fluoro-N-[4-me... 2 5
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Platelet-derived growth factor receptor beta and Macrophage co... 1 4
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5
Gonadotropin-releasing hormone receptor ligand 1-[(2R)-2-amino... 1 1
Coagulation factor X and Prothrombin inhibitor 3-[4-carbamimid... 3 0
Coagulation factor X inhibitor 3-Oxybenzamide 15 family 1 1
Fatty-acid amide hydrolase 1 and Monoglyceride lipase inhibito... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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