CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13743
Family Name Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lck inhibitor 4-[[4-benzyl-6-[(6-methoxy-1,3-benzothiazol-2-yl)amino]pyrimidin-2-yl]amino]cyclohexan-1-ol family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00377472 Functional Category Bioactive
Superfamily Voltage-gated sodium channel Ligand Riluzole Superfamily
Class Class 310

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Transient receptor potential cation channel subfamily V member... 42 32
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 7
Mu-type opioid receptor and Nitric oxide synthase, brain ligan... 3 0
LIM domain kinase 2 and LIM domain kinase 1 inhibitor N-[5-[6-... 1 22
Cyclin-dependent kinase 6 and Cyclin-dependent kinase 4 inhibi... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
Aurora kinase B and Tyrosine-protein kinase ITK/TSK inhibitor ... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 5 0
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 2
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
Prelamin-A/C and Ferritin light chain inhibitor F2515-0224 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00423999 CHEMBL2441275 Bioactive 4-[[4-benzyl-6-[(5-methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl]amino]cyclohexan-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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