CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13746
Family Name Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lck inhibitor 4-[[4-benzyl-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino]cyclohexan-1-ol family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00127117 Functional Category Bioactive
Superfamily Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lck Binder Superfamily
Class Class 3543

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Tyrosine-protein kinase JAK2 and Potassium voltage-gated chann... 1 0
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 2 0
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Cyclin-dependent kinase 6 and Cyclin-dependent kinase 4 inhibi... 1 0
CX3C chemokine receptor 1 and C-X-C chemokine receptor type 2 ... 7 4
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Aurora kinase B and Tyrosine-protein kinase ITK/TSK inhibitor ... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 5 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 2 2
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
Transient receptor potential cation channel subfamily V member... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Vascular endothelial growth factor receptor 2 and Cyclin-depen... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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