CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13748
Family Name Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor 4-[[4-[difluoro-(4-fluorophenyl)methyl]-6-(isoquinolin-3-ylamino)pyrimidin-2-yl]amino]cyclohexan-1-ol family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00160785 Functional Category Bioactive
Superfamily Adenosine receptor A1 Ligand SLV320 Superfamily
Class Class 1134

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
Adenosine receptor A1 Ligand SLV320 Family 6 79
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
C-Jun N-terminal kinase Inhibitor CC-930 Family 2 9
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
Transient receptor potential cation channel subfamily V member... 4 0
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0074... 2 3
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 1
Transient receptor potential cation channel subfamily V member... 5 1
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
Mitogen-activated protein kinase 14 inhibitor 4-(4-fluoropheny... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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