CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13757
Family Name Histamine receptor H3 ligand N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]cyclopropanecarboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00424045 Functional Category Bioactive
Superfamily Histone deacetylase 2 and Histone deacetylase 1 Binder Superfamily
Class Class 1971

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Androgen receptor Ligand 6-n-propyl -4-trifluoromethylquinolin... 29 13
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-nitro-2,3-dihyd... 2 6
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-nitrophenyl)... 3 0
Histamine receptor H3 ligand N-[2-methyl-4-[(3S)-3-[(2S)-2-met... 10 7
Histamine receptor H3 ligand N-[2-methyl-4-[(3S)-3-[(2S)-2-met... 1 0
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
5-hydroxytryptamine receptor 4 ligand 2-oxo-N-[(1R,5S)-8-(2-pi... 13 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424045 CHEMBL2441646 Bioactive N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]cyclopropanecarboxamide
CFAMM00424044 CHEMBL2441653 Bioactive 2-cyclopentyl-N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27702 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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