CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13768
Family Name Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-2 inhibitor N'-[3-[3-(furan-2-yl)phenyl]pyrazolo[1,5-a]pyrimidin-5-yl]ethane-1,2-diamine family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00151399 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand GW876008 Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand ZM-241... 2 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Mitogen-activated protein kinase 14 Inhibitor CP-808844 Family 39 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 8 0
Adenosine receptor A3 and Adenosine receptor A2b ligand CHEMBL... 5 0
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difl... 7 9
Adenosine receptor A2a ligand 5-[[[(2R)-1-[(2-chloropyridin-4-... 5 0
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Vascular endothelial growth factor receptor 1 and Vascular end... 11 38
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Vascular endothelial growth factor receptor 2 ligand AGN-PC-04... 8 1
Tyrosine-protein kinase JAK2 inhibitor (2R)-2-[4-[[8-(4-methox... 2 0
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Adenosine receptor A2a ligand 8-(furan-2-yl)-3-[2-[4-(1,3-thia... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Adenosine receptor A2a ligand SureCN8368237 family 1 0
Mitogen-activated protein kinase 14 and Dual specificity mitog... 1 3
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 2 2
Glucokinase inhibitor AGN-PC-03ZE5E family 1 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 0
Succinate receptor 1 and 2-oxoglutarate receptor 1 ligand 2-[4... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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