CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13769
Family Name Renin inhibitor (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[3-(3-oxopyrido[4,3-b][1,4]thiazin-4-yl)propanoylamino]-3-phenylpropanoyl]amino]pentanamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00424097 Functional Category Bioactive
Superfamily Pol polyprotein and Cathepsin B Binder Superfamily
Class Class 134

Cousin Family NamesSeedsMembers
Renin Inhibitor Remikiren Family 100 126
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor AC1LAD48 family 19 5
Renin and Cathepsin D inhibitor tert-butyl N-[(2R)-1-[[3-[[(2R... 19 4
Renin and Pepsin A inhibitor [(2S)-1-[[(2R)-1-[[(2S,3R)-1-cycl... 2 2
Renin inhibitor propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imid... 4 0
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
Renin inhibitor tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4... 2 2
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3


External ID

Functional Category

Molecule Name

CFAMM00424099 CHEMBL24423 Bioactive (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[3-(2-oxopyrido[2,3-b][1,4]thiazin-1-yl)propanoylamino]-3-phenylpropanoyl]amino]pentanamide
CFAMM00424098 CHEMBL284570 Bioactive (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-3-phenyl-2-[3-(1,1,3-trioxopyrido[4,3-b][1,4]thiazin-4-yl)propanoylamino]propanoyl]amino]pentanamide
CFAMM00424097 CHEMBL26510 Bioactive (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[3-(3-oxopyrido[4,3-b][1,4]thiazin-4-yl)propanoylamino]-3-phenylpropanoyl]amino]pentanamide
CFAMM00424100 CHEMBL284569 Bioactive (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[3-(2-oxopyrido[3,4-b][1,4]thiazin-1-yl)propanoylamino]-3-phenylpropanoyl]amino]pentanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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