CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13776
Family Name Transient receptor potential cation channel subfamily V member 1 ligand SureCN2529513 family
No. of Seeds 22 No. of Other Members 3
Family Centroid CFAMM00424170 Functional Category Bioactive
Superfamily Prelamin-A/C and Ferritin light chain Binder Superfamily 3
Class Class 2958

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 8
Transient receptor potential cation channel subfamily V member... 57 4
Transient receptor potential cation channel subfamily V member... 2 0
Transient receptor potential cation channel subfamily V member... 2 4
Prothrombin inhibitor SureCN6057665 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424173 CHEMBL2442917 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(2-methylcyclohexyl)sulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424160 CHEMBL2442920 Bioactive N-[[2-(cyclohexylmethylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424166 CHEMBL2442928 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(2-phenylethylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424159 CHEMBL2442921 Bioactive N-[[2-[(4-chlorophenyl)methylsulfanyl]-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424172 CHEMBL2442916 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(4-methylcyclohexyl)sulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424152 CHEMBL2442924 Bioactive N-[[2-[(2-chlorophenyl)methylsulfanyl]-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424158 CHEMBL2442903 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(3-pyrrolidin-1-ylpropylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424171 CHEMBL2442912 Bioactive (2S)-N-[[2-cyclohexylsulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424151 CHEMBL2442925 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[6-(trifluoromethyl)-2-[[3-(trifluoromethyl)phenyl]methylsulfanyl]pyridin-3-yl]methyl]propanamide
CFAMM00424157 CHEMBL2442896 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-hexylsulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424170 CHEMBL2442911 Bioactive SureCN2529513
CFAMM00424163 CHEMBL2442898 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(2,2,2-trifluoroethylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424156 CHEMBL2442897 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(3-methylbutylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424169 CHEMBL2442910 Bioactive N-[[2-cyclopentylsulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424162 CHEMBL2442899 Bioactive N-[[2-(3-bromopropylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424175 CHEMBL2442919 Bioactive N-[[2-(4-tert-butylcyclohexyl)sulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424155 CHEMBL2442894 Bioactive N-[[2-butylsulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424168 CHEMBL2442904 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-(3-piperidin-1-ylpropylsulfanyl)-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424161 CHEMBL2442922 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-[(4-methylphenyl)methylsulfanyl]-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424174 CHEMBL2442918 Bioactive N-[[2-(4-ethylcyclohexyl)sulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-2-[3-fluoro-4-(methanesulfonamido)phenyl]propanamide
CFAMM00424154 CHEMBL2442895 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-pentylsulfanyl-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
CFAMM00424167 CHEMBL2442905 Bioactive 2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-[3-(4-methylpiperidin-1-yl)propylsulfanyl]-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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