CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13785
Family Name Coagulation factor X and Cationic trypsin inhibitor 4-(diaminomethylidene)-2-[(E)-3-[4-(1-methylpiperidin-4-yl)oxy-3-(trifluoromethyl)anilino]prop-1-enyl]cyclohexa-2,5-dien-1-one family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00424246 Functional Category Bioactive
Superfamily Cationic trypsin and Coagulation factor X Binder Superfamily 3
Class Class 2196

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor YM60828 Family 8 6
Coagulation factor X and Cationic trypsin inhibitor 4-[[(E)-3-... 1 3
Coagulation factor X and Cationic trypsin inhibitor 3-[(E)-3-[... 3 2
Coagulation factor X and Cationic trypsin inhibitor ethyl 5-[[... 1 0
Coagulation factor X and Cationic trypsin inhibitor 4-[N-[(E)-... 7 0


External ID

Functional Category

Molecule Name

CFAMM00424246 CHEMBL24956 Bioactive 4-(diaminomethylidene)-2-[(E)-3-[4-(1-methylpiperidin-4-yl)oxy-3-(trifluoromethyl)anilino]prop-1-enyl]cyclohexa-2,5-dien-1-one
CFAMM00424244 CHEMBL24433 Bioactive 4-[4-[[(E)-3-[3-(diaminomethylidene)-6-oxocyclohexa-1,4-dien-1-yl]prop-2-enyl]amino]-2-(trifluoromethyl)phenoxy]piperidine-1-carboxamide
CFAMM00424242 CHEMBL423656 Bioactive 4-(diaminomethylidene)-2-[(E)-3-[4-(1-ethanimidoylpiperidin-4-yl)oxy-3-(trifluoromethyl)anilino]prop-1-enyl]cyclohexa-2,5-dien-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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