CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13792
Family Name Nitric oxide synthase, inducible inhibitor SureCN2258300 family
No. of Seeds 2 No. of Other Members 24
Family Centroid CFAMM00424288 Functional Category Bioactive
Superfamily Substance-P receptor and Nitric oxide synthase, brain Binder Superfamily
Class Class 2845

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand 3-benz... 1 6
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 9 24
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Cathepsin K and Potassium voltage-gated channel subfamily H me... 3 1
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
Substance-P receptor and Sodium-dependent serotonin transporte... 11 4
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3


External ID

Functional Category

Molecule Name

CFAMM00424289 CHEMBL607146 Bioactive 6-{[(3r,4r)-4-(2-{[2-(3-Fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-Yl]methyl}-4-Methylpyridin-2-Amine
CFAMM00424288 CHEMBL2447968 Bioactive SureCN2258300

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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