CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13794
Family Name Trans-2-enoyl-ACP reductase II inhibitor AGN-PC-01LWZK family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00424302 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H3 receptor Binder Superfamily 7
Class Class 392

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Aurora kinase A inhibitor AGN-PC-07ZZEH family 2 4
Aurora kinase A inhibitor 2-[4-[6-chloro-2-[4-(morpholin-4-ylm... 1 2
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZXHN fa... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 2 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
TGF-beta receptor type-1 ligand 6-[(5E)-5-(4-methyl-3H-1,3-thi... 22 9
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424302 CHEMBL244805 Bioactive AGN-PC-01LWZK
CFAMM00424304 CHEMBL390894 Bioactive AGN-PC-01LX5W
CFAMM00424303 CHEMBL392732 Bioactive 1-[[5-(3,4-dichlorophenyl)-1H-imidazol-2-yl]methyl]-3-(5-pyridin-2-ylsulfanyl-1,3-thiazol-2-yl)urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543