CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1384
Family Name Calcitonin gene-related peptide type 1 receptor ligand N,N-dimethyl-4-[3-[2-[[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-2-oxobenzimidazol-1-yl]butanamide family
No. of Seeds 12 No. of Other Members 32
Family Centroid CFAMM00322782 Functional Category Bioactive
Superfamily Aldose reductase and Calcitonin gene-related peptide type 1 receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Calcitonin gene-related peptide type 1 receptor and Dual speci... 8 4
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Calcitonin gene-related peptide type 1 receptor and Dual speci... 4 0


External ID

Functional Category

Molecule Name

CFAMM00322766 CHEMBL519421 Bioactive 2-[3-[2-(dimethylamino)-2-oxoethyl]-4,6-dimethyl-2-oxobenzimidazol-1-yl]-N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide
CFAMM00322779 CHEMBL453644 Bioactive CHEMBL453644
CFAMM00322772 CHEMBL488082 Bioactive methyl 2-[5,7-dimethyl-3-[2-[[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-2-oxobenzimidazol-1-yl]acetate
CFAMM00322777 CHEMBL471358 Bioactive 2-(4,6-dimethyl-2-oxo-3H-benzimidazol-1-yl)-N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide
CFAMM00322783 CHEMBL455674 Bioactive CHEMBL455674
CFAMM00322782 CHEMBL455670 Bioactive N,N-dimethyl-4-[3-[2-[[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-2-oxobenzimidazol-1-yl]butanamide
CFAMM00322755 CHEMBL1162991 Bioactive CHEMBL1162991
CFAMM00322768 CHEMBL466192 Bioactive CHEMBL466192
CFAMM00322781 CHEMBL487068 Bioactive 2-[5,7-dimethyl-3-[2-[[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-2-oxobenzimidazol-1-yl]acetamide
CFAMM00322738 CHEMBL530116 Bioactive N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(3,4,6-trimethyl-2-oxobenzimidazol-1-yl)acetamide
CFAMM00322767 CHEMBL455458 Bioactive CHEMBL455458
CFAMM00322780 CHEMBL453643 Bioactive CHEMBL453643

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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