CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13847
Family Name Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ligand AGN-PC-02TCFK family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00178929 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor Ligand Upidosin Superfamily
Class Class 1677

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor Ligand Epidepride Family 31 66
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 13 20
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 4 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor 6,7-d... 1 29
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 9
DNA-dependent protein kinase catalytic subunit inhibitor 5-hyd... 1 7
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 1
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Multidrug resistance protein 1 inhibitor (1R)-2-[4-(2-methoxyp... 2 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand 7-[3... 1 12


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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