CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13848
Family Name Prothrombin inhibitor (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R,3S)-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-3-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide family
No. of Seeds 8 No. of Other Members 7
Family Centroid CFAMM00424690 Functional Category Bioactive
Superfamily Prothrombin Inhibitor Oscillarin Superfamily
Class Class 1444

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelagatran Family 5 48
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Prothrombin Inhibitor Oscillarin Family 1 3
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anil... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424694 CHEMBL567464 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R)-3,3-dicyclohexyl-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424700 CHEMBL392197 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-cyclohexyl-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]acetyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424693 CHEMBL246295 Bioactive (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R,3R)-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carboxamide
CFAMM00424698 CHEMBL565466 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R,3R)-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-3-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424691 CHEMBL568275 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2S,3R)-3-chloro-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-4-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424690 CHEMBL391986 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R,3S)-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-3-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424689 CHEMBL246703 Bioactive (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2S,3S)-3-chloro-2-[[(2R)-2-hydroxy-3-phenylpropanoyl]amino]-4-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
CFAMM00424688 CHEMBL79705 Bioactive (3S,6R,8aS)-6-benzyl-N-[(4-carbamimidoylphenyl)methyl]-6-hydroxy-5-oxo-1,2,3,7,8,8a-hexahydroindolizine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27649 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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