CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13852
Family Name Histamine H3 receptor and Sodium-dependent serotonin transporter ligand AGN-PC-00DS0V family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00179771 Functional Category Bioactive
Superfamily Histamine H3 receptor and Sodium-dependent serotonin transporter Binder Superfamily 3
Class Class 280

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Substance-P receptor Ligand Ezlopitant Family 10 207
CORT-108297 family 46 44
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)met... 17 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 9
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Histamine H3 receptor ligand SureCN5093910 family 3 16
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-(4-... 2 6
Lysosomal Pro-X carboxypeptidase inhibitor 1-(3,5-dichlorophen... 1 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 1 1
Histamine H3 receptor ligand SureCN6071181 family 2 1
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Histamine H3 receptor ligand AGN-PC-0765YW family 1 4
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (2R,... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Transporter and Sodium-dependent serotonin transporter inhibit... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Histamine H3 receptor and Histamine H1 receptor ligand AGN-PC-... 1 0
Sodium-dependent dopamine transporter and Transporter inhibito... 4 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424726 CHEMBL246331 Bioactive SureCN1034272

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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