CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13863
Family Name Histamine H3 receptor ligand 4-[6-(2-pyrrolidin-3-ylethyl)naphthalen-2-yl]benzonitrile family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00274979 Functional Category Bioactive
Superfamily Histamine H3 receptor Binder Superfamily 10
Class Class 2510

Cousin Family NamesSeedsMembers
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
5-hydroxytryptamine receptor 7 ligand 5-methyl-6-(6-methyl-5,6... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 5
Histamine H3 receptor ligand SureCN1641166 family 3 0
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 0
Histamine H3 receptor ligand SureCN1640926 family 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48682 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543