CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13868
Family Name Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-gated channel subfamily H member 2 ligand 6-[1-hydroxy-2-[4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl]propyl]-3,4-dihydro-1H-quinolin-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00424828 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily
Class Class 833

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 1 5
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 4 9
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1


External ID

Functional Category

Molecule Name

CFAMM00424829 CHEMBL247841 Bioactive 6-[1-hydroxy-2-[4-hydroxy-4-[3-(phenoxymethyl)phenyl]piperidin-1-yl]propyl]-3,4-dihydro-1H-quinolin-2-one
CFAMM00424828 CHEMBL246818 Bioactive 6-[1-hydroxy-2-[4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl]propyl]-3,4-dihydro-1H-quinolin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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