CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13878
Family Name Histamine H3 receptor and Sodium-dependent serotonin transporter ligand 4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-piperidin-1-ylpropoxy)-3,4-dihydro-1H-2,6-naphthyridine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00147946 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-4 and Cytochrome P450 1A2 Binder Superfamily
Class Class 1004

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Squalene synthase Inhibitor ER-119884 Family 2 3
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 3 24
Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 ... 4 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Metabotropic glutamate receptor 5 ligand 2-chloro-6-[(2-methyl... 1 4
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 7
Sodium-dependent serotonin transporter and Histamine H3 recept... 6 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 8
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Bifunctional epoxide hydrolase 2 and Voltage-dependent L-type ... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42616 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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