CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13888
Family Name Serine/threonine-protein kinase Chk1 inhibitor SureCN4817112 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00424948 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 5013

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 12 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN4806204 f... 13 7
Serine/threonine-protein kinase Chk1 inhibitor SureCN4814441 f... 4 1
Serine/threonine-protein kinase Chk1 and Aurora kinase B inhib... 14 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00424948 CHEMBL247396 Bioactive SureCN4817112
CFAMM00424947 CHEMBL251755 Bioactive 5-[7-(3-imidazol-1-ylpropoxy)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl]pyridine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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