CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13899
Family Name Thrombopoietin receptor ligand N-[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-4-[[6-(3-hydroxyazetidin-1-yl)pyrimidin-4-yl]amino]benzamide family
No. of Seeds 2 No. of Other Members 14
Family Centroid CFAMM00425030 Functional Category Bioactive
Superfamily Thrombopoietin receptor and Follicle-stimulating hormone receptor Binder Superfamily
Class Class 170

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 37 10
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Metabotropic glutamate receptor 5 and Cytochrome P450 3A4 liga... 1 14
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Hepatocyte growth factor receptor ligand AGN-PC-077PZW family 1 0
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425024 CHEMBL429295 Bioactive AGN-PC-069CS7
CFAMM00425030 CHEMBL248218 Bioactive N-[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-4-[[6-(3-hydroxyazetidin-1-yl)pyrimidin-4-yl]amino]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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