CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM139
Family Name Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzylsulfanyl-2-[[2-(cyclohexylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-N-hydroxybutanamide family
No. of Seeds 10 No. of Other Members 32
Family Centroid CFAMM00255102 Functional Category Bioactive
Superfamily Interstitial collagenase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3087

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Collagenase 3 and Interstitial collagenase inhibitor AGN-PC-01... 10 1
Cathepsin K inhibitor SureCN6578603 family 1 3
Cathepsin K and Cathepsin S inhibitor SureCN8247244 family 2 0
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor AC1L4BQ... 3 0
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)p... 2 4
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Disintegrin and metalloproteinase domain-containing protein 17... 4 2
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Disintegrin and metalloproteinase domain-containing protein 17... 6 12
72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl... 11 5
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 6 0
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Bone morphogenetic protein 1 inhibitor benzyl N-[(4R)-4-[1,3-b... 6 25
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 5 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulf... 2 11
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 8 6
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(3S)-2... 2 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 0
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[2-(3-methoxyp... 1 0
Bone morphogenetic protein 1 inhibitor (2R)-2-[(4-bromophenyl)... 1 4
Beta-lactamase and Histone-lysine N-methyltransferase 2A inhib... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307920 CHEMBL47468 Bioactive (2R)-2-[[2-(benzhydrylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-4-benzylsulfanyl-N-hydroxybutanamide
CFAMM00307902 CHEMBL420656 Bioactive 2-[[2-(benzhydrylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-4-benzylsulfanyl-N-hydroxybutanamide
CFAMM00307908 CHEMBL102798 Bioactive 2-[[2-(benzylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-4-benzylsulfanyl-N-hydroxybutanamide
CFAMM00307894 CHEMBL322619 Bioactive 4-benzylsulfanyl-2-[[2-(dicyclohexylmethylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-N-hydroxybutanamide
CFAMM00307914 CHEMBL323090 Bioactive 4-benzylsulfanyl-2-[[2-(cyclohexylmethylamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-N-hydroxybutanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543