CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13907
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2S)-1-[(3R,4R)-4-amino-1-[(4-cyanophenyl)methyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00425067 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 Binder Superfamily 2
Class Class 1787

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 2 0
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-4-(1,3-dih... 3 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 3
Dipeptidyl peptidase 8 inhibitor (2S)-2-amino-4-[4-[bis(4-fluo... 2 9
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Dipeptidyl peptidase 4 inhibitor 4-cyano-N-[4-[(2S)-2-cyanopyr... 1 1
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
Dipeptidyl peptidase 4 inhibitor 4-[4-[(3S,5S)-5-(1,3-thiazoli... 3 2
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor Su... 1 1
Dipeptidyl peptidase 4 inhibitor SureCN14523901 family 7 1
Dipeptidyl peptidase 4 inhibitor (2S,4S)-4-fluoro-1-[2-[[(E)-2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425069 CHEMBL438520 Bioactive (2S)-1-[(3R,4R)-4-amino-1-[(3-cyano-4-fluorophenyl)methyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00425068 CHEMBL249601 Bioactive (2S)-1-[(3R,4R)-4-amino-1-[1-(4-cyanophenyl)ethyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00425067 CHEMBL248599 Bioactive (2S)-1-[(3R,4R)-4-amino-1-[(4-cyanophenyl)methyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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