CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13920
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (1R)-2-[(3R,4R)-4-amino-1-[1-[4-(1,2,4-triazol-1-yl)phenyl]ethyl]pyrrolidine-3-carbonyl]cyclopentane-1-carbonitrile family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00425166 Functional Category Bioactive
Superfamily Prothrombin and Beta-lactamase Binder Superfamily 2
Class Class 3077

Cousin Family NamesSeedsMembers
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 2 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425166 CHEMBL400532 Bioactive (1R)-2-[(3R,4R)-4-amino-1-[1-[4-(1,2,4-triazol-1-yl)phenyl]ethyl]pyrrolidine-3-carbonyl]cyclopentane-1-carbonitrile
CFAMM00425165 CHEMBL248794 Bioactive (2S)-1-[(3R,4R)-4-amino-1-[[4-(3-methyl-1,2,4-triazol-1-yl)phenyl]methyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile
CFAMM00425164 CHEMBL250620 Bioactive (1R)-2-[(3R,4R)-4-amino-1-[[2-methyl-4-(1,2,4-triazol-1-yl)phenyl]methyl]pyrrolidine-3-carbonyl]cyclopentane-1-carbonitrile
CFAMM00425163 CHEMBL399525 Bioactive (2S)-1-[(3R,4R)-4-amino-1-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]pyrrolidine-3-carbonyl]pyrrolidine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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