CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13925
Family Name Serine/threonine-protein kinase Chk1 inhibitor SureCN4298966 family
No. of Seeds 10 No. of Other Members 1
Family Centroid CFAMM00425187 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 8
Class Class 4994

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Mitogen-activated protein kinase 14 and Mast/stem cell growth ... 4 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
Calcitonin gene-related peptide type 1 receptor ligand 2-[(7-m... 3 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Rho-associated protein kinase 2 inhibitor 2-[(3S,4R)-4-(4-fluo... 9 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4288215 f... 3 0
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Cathepsin F and Cruzipain inhibitor (2S)-N-[(1S)-1-cyano-2-phe... 1 0


External ID

Functional Category

Molecule Name

CFAMM00425191 CHEMBL428409 Bioactive SureCN4291853
CFAMM00425189 CHEMBL249044 Bioactive SureCN4296246
CFAMM00425196 CHEMBL249834 Bioactive SureCN4297110
CFAMM00425188 CHEMBL249240 Bioactive SureCN4289057
CFAMM00425195 CHEMBL250033 Bioactive SureCN4291075
CFAMM00425187 CHEMBL401156 Bioactive SureCN4298966
CFAMM00425194 CHEMBL400127 Bioactive SureCN4296222
CFAMM00425193 CHEMBL249224 Bioactive SureCN4287965
CFAMM00425185 CHEMBL249632 Bioactive SureCN4292968
CFAMM00425192 CHEMBL400323 Bioactive SureCN4291494

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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